Hypersensitivity and cross-reactivity to cisplatin and carboplatin

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hypersensitivity and cross-reactivity to cisplatin and carboplatin.

abstract cisplatin was the first of the platinum drugs. second-generation platinum derivative was carboplatin that its efficacy in the treatment of many malignancies is equal to cisplatin, and its toxicity profile is more favorable. here we report on a 50-year-old woman with a history of cervix cancer who developed a severe hypersensitivity reaction (hsr) to carboplatin. she was admitted to the...

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Immediate hypersensitivity to quinolones: moxifloxacin cross-reactivity.

INTRODUCTION Immediate hypersensitivity reactions to quinolones are rare. Moxifloxacin is an quinolone chemically different from other fluoroquinolones. We report 6 patients diagnosed with hypersensitivity to different fluoroquinolones in whom the response to moxifloxacin and cross-reactivity with other quinolones was studied. MATERIAL-METHODS An allergenic study was made by prick and intrade...

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Cross-reactivity in drug hypersensitivity reactions to sulfasalazine and sulfamethoxazole.

BACKGROUND Sulfonamides are generally classified into 2 groups: antibiotics and non-antibiotics. Recent studies showed that patients allergic to sulfonamide antibiotics do not have a specific risk for an allergy to sulfonamide non-antibiotic. However, the anti-inflammatory drug sulfasalazine represents an important exception. Used in rheumatic diseases, it is classified as a non-antibiotic sulf...

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Carboplatin hypersensitivity reactions.

Carboplatin is used widely to treat cancers such as lung, breast, and ovarian. Hypersensitivity reactions (HSRs) to carboplatin can occur, often after numerous doses. The reactions can range from mild to life threatening. Oncology nurses witness the reactions and are instrumental in providing interventions to assist patients. Symptoms include flushing, rashes, itchy palms, nausea, difficulty br...

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ژورنال

عنوان ژورنال: Journal of Emergency Practice and Trauma

سال: 2015

ISSN: 2383-4544

DOI: 10.15171/jept.2016.09